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These proteases can cleave inactive forms of transcription factors, converting them into their active forms, which can then bind to DNA and regulate gene expression

In a study of triple-negative breast cancer (TNBC), it was found that when combined with the SLC7A5 blocker JPH203 and an anti-programmed cell death 1 (PD-1) antibody, it significantly inhibited cell proliferation, invasion, and migration, increased infiltration of CD8 + T cells, and suppressed tumor immune escape [106, 107]

The third group of chemotherapeutics is formed by anti-mitotic agents, which act on microtubules

Find articles by Rantakari, P

Mechanical complications of myocardial infarction, advanced heart failure, valvular heart disease, myocarditis, cardiomyopathies, and pericardial diseases are other important causes [Table 1]

This paper provides a theoretical framework for understanding and potentially treating VaD-related neuronal injury through the investigation of ferroptosis mechanisms, the biological functions of HO-1, and its role in regulating ferroptosis