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doi:10.1038/srep20382

Biotechnol Lett 43:407414

Time interval between sample withdrawal and freezing was within 1,5-8 hours with average of 5 hours

In each approach, the first guide RNA (gRNA) targeted Venus while the second gRNA targeted either a nontargeting control sequence not present in the genome, or the gene of interest (GOI)

21 A recent study demonstrated the expression of TGF-1 and the activation of TGF- signaling in perinecrotic areas after APAP overdose in mice and in APAP-induced ALF patients, which was associated with impaired liver regeneration and hepatocyte senescence