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Small molecule drugs have always been the preferred molecules for the development of intracellular target drugs due to their good stability, high oral bioavailability, and enhanced cell penetrability

Targeting Glycolysis Delays the Onset of T1D in an Adoptive Transfer Model Based on the ability of PFK15 treatment to reduce BDC2.5 T cell responses, we examined the impact of glycolysis inhibition on the onset of diabetes using an adoptive transfer model ( Figure 3A )

In a mouse model, Hcy has been shown to exacerbate -amyloid plaque formation, the process related to the onset of Alzheimers disease [85]

A double-blind study showed GSH reduced cisplatin toxicity and improved quality of life in ovarian cancer patients

Theres evidence that long-term or severe sleep deprivation can cause brain damage

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