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& Jalovaara, P

The real story is the physiology underneath

GR enzyme maintains the cellular reduced GSH level and plays a central role in cell defense against reactive oxygen species

Copper Load Assessment: Is Accumulation a Real Concern

This finding links 4HNE to ferroptosis, as evidenced by lipid peroxidation, iron accumulation, nuclear translocation of NRF2, decreased GPX4 protein levels, and increased expression of ferroptotic markers, confirming that 4HNE acts as an inducer of ferroptosis [54]