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doi: 10.1016/j.mce.2014.05.008 305 ZhangX-LLiuNWengS-FWangH-S

Research shows these peptides normalize melatonin release, boosting nighttime levels and shifting its peak to 3:00 AM, as seen in younger individuals

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Chronological (Intrinsic) Aging Intrinsic or chronological aging is a natural process with the passage of time that causes inflammation with the production of reactive oxygen species (ROS) resulting in oxidative stress from cellular metabolism, which results in a loss of skin homeostasis [9, 10, 14] (Fig