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211,212 For example, age-related upregulation of CXCR4 leads to mislocalization of Tfh cells to the dark zone, along with a significant reduction in the follicular dendritic cell (FDC) network area and a marked decrease in the number of plasma cells

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Blood 92:25942596 Hammerman SI, Kourembanas S, Conca TJ, Tucci M, Brauer M, Farber HW (1997) Endothelin-1 production during the acute chest syndrome in sickle cell disease

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