glutathione synthase hydroxymethyl production by Saccharomyces cerevisiae: current state and perspectives | Applied Microbiology and Biotechnology Glutathione-Related Enzymes and Proteins: A

PMID: 27847966 | doi:10.1007/s00109-016-1488-y Seiwerth S et al

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This important preclinical study showed that ketamine and other NMDAR antagonists produce fast-acting antidepressant-like effects in mouse models that depend on the rapid synthesis of BDNF via a mechanism that includes the deactivation of eEF2 kinase

This pathway may be involved in MDR by inducing PI3K/AKT/NF- activation, which results in cyclin D1 transformation, G1/S phase protein expression, and cell cycle acceleration [42]

Consistent with the results from GSH2ox #2 and smt15-1 strains, the synchronized GSH2ox #3 cells were able to divide up to three times or even four times despite their relatively small-sized mothers (Supplemental Figure S2A) while the vast majority of the wild-type mothers only divided twice (Supplemental Figure S2B)

Downregulation of the osmolyte transporters SMIT and BGT1 by AMP-activated protein kinase