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Using 13 C-NMR, this metabolic flux of lactate from astrocyte to neuron can be measured noninvasively in the human brain (Bouzier-Sore et al., 2007): [mathematical modeling] can give a coherent, quantitative framework for the discussion, suggest possible mechanisms or, conversely, emphasize the contradictions or implausibility or some hypotheses. An example of the argument about the possible ambiguity of mathematical modeling is given by Genc et al

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12 Respecto a la suplementacin con L-carnitina, se aplic Cardispan I.V., que es L-carnitina 50 mg/ kg/sesin y se prepar en un mililitro de solucin salina, en una jeringa de 20 mL, 30 minutos antes de terminar cada sesin de hemodilisis y se aplic sobre la lnea venosa.11 El cardispan fue proporcionado por la Unidad Mdica de Alta Especialidad, UMAE Hospital Gineco/pediatra 48 (UMAE 48) y fue aplicado por las enfermeras del rea de hemodilisis peditrica