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doi: 10.1007/s10815-019-01555-1 259 MaieseK

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In addition, TAMs express CCL22, attract Tregs to increase the production of molecules such as PD-L1, disrupt T-cell metabolism by expressing ARG1, and deprive T cells of L-arginine, a key nutrient for T-cell growth 270

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Its essential for producing glutathione

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Wang W, Xu MJ, Cai Y, Zhou Z, Cao H, Mukhopadhyay P, et al

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Hypoxic tumor microenvironment: implications for cancer therapy

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The addition of metabolic support further enhances how the body processes and utilizes energy

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