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Gut microbes can use carnitine and acylcarnitine as carbon sources, nitrogen sources, osmotic protectants or electron acceptors, but the gut microbiota cannot synthesize carnitine itself, and the mitochondrial function of acylcarnitine produced by carnitine palmitoyltransferase has not been observed in prokaryotes [230]

Research indicates that free iron abundance promotes lipid peroxidation through the accumulation of reactive oxygen species (ROS) and the activation of iron-containing enzymes ( Figure 1 )

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