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Chronic psychosocial stress in mice elevates ROS in GCs, impairing follicular development and promoting apoptosis [24, 98]

Emerging evidence indicates that the KD modulates the composition of gut microbiota

Estrogen-induced gene expression is one example of how this pathway influences gene regulation (Hao et al., 2018) The essential mechanism relies on the catalytic function of 8-oxoguanine DNA glycosylase-1 (OGG1) and the structural modifications induced by topoisomerase IIb on the promoter