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Research uses this combination to investigate peptide driven effects on extracellular matrix remodeling, cell migration, cytoskeletal organization, and gene expression patterns related to tissue structure and repair, with all applications restricted to laboratory research use only

2.1 Renal Impairment Study 2.1.1 Study Population Male and female participants of non-childbearing potential were eligible for inclusion in the renal impairment study if they were aged between 18 and 80 years with a body mass index (BMI) between 20 and 39.9 kg/m 2 and a body weight 60 kg at screening

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Hepatic stellate cells, characterized by DES and VIM expressions, are central to liver fibrosis and extracellular matrix remodeling 34,36

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Kh., Bondarev, I