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Abdominal pain is listed as the most common side effect, and few cases of gastrointestinal bleeding are also described (Fennell et al., 2007)

The increased fibroblasts and keratinocyte proliferation help produce more collagen and form the extracellular matrix needed for tissue repair

For the vascular side, GHK-Cu promotes angiogenesis through VEGF and bFGF expression, improves blood vessel integrity, and supports microcirculation

Ketone body 3-Hydroxybutyrate ameliorates atherosclerosis via receptor Gpr109a-mediated calcium influx

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Aggregates form when peptides interact through hydrophobic surfaces, -sheet formation, or disulfide bond scrambling