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However, the expanding toolkit of VLP engineering strategiesspanning genetic fusion, modular conjugation, and nucleic acid encapsulationcreates a critical need for a rational selection framework to match technological strengths with specific vaccine objectives

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- Lithium: because it reduces the renal clearance and increases lithium levels in plasma which increases the risk of lithium toxicity

Managing vitamin B12 deficiency in cases of pernicious anemia requires lifelong B12 supplementation, as the autoimmune destruction of gastric parietal cells results in an irreversible lack of intrinsic factors

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It also helps form red blood cells that carry oxygen throughout the body, which is why a deficiency can cause symptoms such as fatigue, weakness, and anemia