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Moreover, genetic inactivation of the tumor suppressor NF2, a frequent tumorigenic event in mesothelioma, renders cancer cells more sensitive to ferroptosis, malignant mutations in NF2YAP signaling can be used to predict the responsiveness of cancer cells to future ferroptosis-inducing therapy [56]

These findings suggest that REST mainly induces ferroptosis, instead of other forms of cell death in the HR model

doi: 10.1016/j.scitotenv.2023.166424 27 DongJ.LiH.WangG.LiH.ZhaoY.LiX.et al

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Magnesium: Relieves stress and promotes relaxation

Urology 1997