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10.1016/j.drudis.2022.01.014 3 AhmadiA.PanahiY.JohnstonT

Methionine is the main precursor of cysteine in liver, which supplies 50% of the cysteine needed for GSH synthesis

Glutathione is vital for detoxifying acetaldehyde, a toxic byproduct of alcohol metabolism, which contributes to oxidative stress and liver damage

Results: By sequencing ~200 randomly selected mutants, we found that transposon insertion is evenly distributed across the bacterial chromosome

- Bc 4 : Tip tc thc hin cc bc chm sc chuyn su tip theo nh: serum, kem dng trng da

Data analysis was performed by a MyiQ software system (Bio-Rad Laboratories), in which C t values were normalized for endogenous reference ( HPRT ) compared with the calibrator (i.e., average C t value of 3 control samples for the fetuses and four control samples for the adult mice)