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Powe DG, Akhtar G, Habashy HO, Abdel-Fatah T, Rakha EA, Green AR, Ellis IO

Acute AMPK activation has exacerbated ischemic brain injury, but the clinical application of metformin reduced the incidence of stroke

Given that IgA nephropathy is the most common glomerular disease and mesangial IgA staining is common, whether these observations are coincidental or there is some association between IgA nephropathy and cosmetics containing mercury is debated

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Therefore, more clinical trials are needed to verify the effectiveness of ferroptosis-based treatments for human diseases