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PD-1/PD-L1 checkpoint-blocking antibodies are thought to act primarily in the tumor microenvironment, where PD-L1 is expressed by tumor cells (174), myeloid cells (168, 203, 204), LECs (94, 95, 98), blood endothelial cells (95), B cells (205, 206), T cells (207), dendritic cells (203) and NK cells (208, 209)

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Reconstitution Best Practices Add bacteriostatic water slowly along the inner vial wall of the lyophilized peptide vial never inject directly onto the lyophilized powder cake, as this can cause local denaturation

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