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Researchers introduced a ketone functional group into the erastin structure to obtain the carbonyl analog imidazole ketone erastin (IKE), which is more effective at inducing ferroptosis [128]

In addition, DOD has stated that the Office of Economic Adjustment, which has significant experience with community economic development and was a key part of the IMCP pilot, will likely play a key role in its implementation

Recognition of oxidized lipids by macrophages and its role in atherosclerosis development

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However, in AML harboring TP53 mutations, DTP cells are arrested in G2/M phases of cell cycle, elimusertib inhibits the expression of the G2/M-phase cell-cycle checkpoints regulators (including cdc25c, p-CDK1, and Cyclin b) to reactivate the cell cycle thereby resensitize to treatments (Kim et al., 2024)