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Long-term safety unknowns Chronic use effects: Most protocols last weeks to months

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Screening of vitamin B12 in children diagnosed as Autism Spectrum Disorder: 3

One is that the effects of electrical stimulation on brain network activity are complex mixtures of activation and inactivation effects that involve activity changes downstream and upstream from the stimulated brain area [292, 293]

Older adults are also at higher risk for a B-12 deficiency because absorption often decreases with age