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Additionally, they point out that hyperhomocysteinemia remains an independent risk factor for thrombosis and stroke after adjustment for established risk factors

In this context, the exploration of ME/CFS pathogenesis has increasingly focused on the microbiome-gut-brain axis, revealing a complex interplay between intestinal dysbiosis and the multifaceted symptomatology of this debilitating condition [10]

For example, the increased dosage of CBS and GCS in our simulation of Down syndrome causes the intracellular concentration of cysteine to decline while the blood concentration increases

Disruption of this homeostatic equilibrium can lead to dysbiosis and consequent metabolic perturbations that are increasingly implicated in the pathogenesis of chronic conditions such as cancer, cardiometabolic disorders, and IBD (187)

MC level in drinking water was regulated to 10 mg/l per day for children

The hexyl substitution on sulfur (KL3) resulted in a high cytotoxicity against host macrophages, indicating a poor therapeutic index