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The non-enzymatic mechanism is driven by the Fenton reaction, which utilizes iron and oxygen to catalyze a chain reaction, leading to the formation of phospholipid hydroperoxides [35]

The results show that the neuropathologic hallmark of AD is also influenced by the release of peroxidation of lipids byproducts

doi: 10.1146/annurev-biochem-061516-045037 80 SiesH.CadenasE

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Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model