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Correlative studies have linked elevated global mtDNA methylation to pathological conditions such as cardiovascular disease, but its specific role in cardiac health and disease is still an area of active investigation

Measure whether daily maternal administration of vitamin B 12 from early pregnancy until 6 months postpartum alters sleep and activity patterns of the infant

Conditions like pernicious anaemia (an autoimmune condition affecting a protein called intrinsic factor vital for B12 absorption), stomach issues (such as from reduced stomach acid or certain medications like proton pump inhibitors), intestinal disorders (like Crohns disease or coeliac disease), or even surgical removal of parts of the small intestine (e.g., gastric bypass surgery) can prevent proper absorption

Excessive or prolonged inflammation damages healthy tissue and delays repair

these measurements were repeated every 4 weeks until week 20, and every 8 weeks thereafter, until week 100 and week 104 (within 3 days either side of scheduled visit day)

Your response to the loading doses was probably because you had a lot of damage and the nerves really needed that B12