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Bretn-Romero & Lamas, 2014

Khoshnoodi J, Sigmundsson K, Cartailler J-P, Bondar O, Sundaramoorthy M, Hudson BG

The resistance across the epithelial layer (TEER) and expression and distributions of the proteins involved in tight junctions (ZO-1, occludin, and claudin-1), receptors responsible for detecting pathogens (TLR2 and TLR4), and molecules that inhibit the TLR signaling pathway increased (A20 and IRAK-M) (186)

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Instead, it quietly blocks the trigger that creates dark brown pigment