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doi: 10.1016/j.cmet.2023.08.005

Therefore, although links between AD and cholesterol metabolism-related genes other than apoE4 seem to support the importance of abnormal cholesterol metabolism in AD pathogenesis, the association between those genes and AD, except for the case of apoE4, remains weak

Interestingly, aged mice exhibited a re-emergence of several youthful phenotypic traits following treatmentincluding increased physical activity, improved cognitive performance, and enhanced fur density

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Results Coordinated consequences of niche remodeling We have previously shown that increased bone marrow adiposity in diabetic mice leads to the depletion of vascular regenerative stem cells 46,47

Washington, DC, USA: 2013