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It was measured in human clinical trials using corneal confocal microscopy, a technique that directly visualizes and quantifies small nerve fiber density

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After 24 h of co-culture with G/D-CuP, NIH/3T3 cells displayed well-spread morphology and high viability, as demonstrated by both 3D and 2D Calcein-AM fluorescence imaging via CLSM (Supplementary Fig

Unlike simple dipeptides, the structure incorporates extended aliphatic side chains and terminal modifications that increase molecular complexity while retaining recognizable peptide-like architecture