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Following an oral dose in dogs of 2.5 mg/kg (1.13 mg/lb), enrofloxacin reached 50% of its maximum serum concentration in 15 minutes and peak serum level was reached in one hour

188 In addition, TRIM21 is also responsible for the polyubiquitination of prohibitin 1 (PHB1), a pleiotropic protein that functions as a tumor suppressor