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Studies using APP/PS1 micea well-established model of Alzheimer's pathologydemonstrate that Dihexa administration restored spatial learning and cognitive functions to near-wildtype levels as measured by Morris water maze performance

In models of hind limb ischemia, it accelerated blood flow recovery and increased vessel density, highlighting its pro-angiogenic properties

[1] Retatrutide (trials): once-weekly subcutaneous administration, starting low (e.g., 2 mg) and escalating to 4, 8, or 12 mg maintenance, with slower titration used to improve tolerability

Pre-registration and blinded assessment , to guard against the selective reporting and evaluator bias that plague small cosmetic studies

Anesth Analg 83:591594 Gasulla J, Calvo DJ (2015) Enhancement of tonic and phasic GABAergic currents following nitric oxide synthase inhibition in hippocampal CA1 pyramidal neurons