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Notably, these regions partially reduced mCTSD levels in earlier experiments, though not below our predefined threshold (Fig

Acknowledgments This work was financially supported by the Ministry of Education, Youth and Sports of the Czech Republic under the INTER-EXCELLENCE program (grant no

In fact, this common transitory colonizer of the human nasopharynx is able to cross the nasopharyngeal epithelial barrier (NEB), entering and replicating in the bloodstream, resulting in septicemia and/or septicemic shock

doi: 10.1093/toxsci/kfn251 110 KafleA.TimilsinaA.GautamA.AdhikariK.BhattaraiA.AryalN

Although the proposed vicious cycle remains a working hypothesis requiring further validation, understanding this interplay may help identify novel biomarkers, stratify patients by metabolic phenotype, and guide precision therapies for HF

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