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2.1.3 In vitro models Detailed cellular level analysis facilitated by in vitro models of tissue injury and induction of IRI have been successfully reported in cell lines of kidney, liver, heart and lung (34)

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Furthermore there is also some limited and inconsistent evidence that changes in transporter activity may contribute to the reductions in UA seen in PD and these are reviewed below

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or (3) a biological licensed under section 351 of the PHS Act (that is, a biological product, including a biosimilar)