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Researchers used Pluronic 127 hydroxypropyl methylcellulose (HPMC) to form thermosensitive gels

This causes bodywide damage to nerve cells, fibers (axons), and coverings (myelin sheaths)

However, the trial vaccine inoculum used was significantly lower than those in previous batches (Chan et al, 2016) (Appendix Fig

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10 However, many human patients with DCM cannot tolerate even very low doses of beta-blockers and demonstrate rapid cardiac decompensation