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4) 35,36,37 , which can subsequently be transaminated to form glycine

Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation

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Dashed arrows indicate negative feedback from circulating T 3 and T 4 to both the hypothalamus and pituitary gland, reducing TRH and TSH secretion

It is tempting to speculate, however, that the ROS-producing reaction may contribute to the long-term stability of SOD1 by preserving the oxidized status of its conserved disulfide in a highly reducing atmosphere of cellular interior