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Indeed, P-15 was found to stimulate the proliferation and differentiation rate as well as the growth factor production of osteoblasts in vitro [113, 137, 189]

[Google Scholar] 170.Francesca M, Marina G, Elena R

Dopaminergic neuronal death, -synuclein aggregates, mitochondrial dysfunction, reactive oxygen species, apoptosis, and neuroinflammation are shown to be the pathological hallmarks of PD [6]

Importantly, even the integrity of BBB can vary among PD patients, altering permeability of therapeutic agents and further complicating the development of effective PLGA nanoparticle therapies 145,146

Khorsandi K, Hosseinzadeh R, Sadat Esfahani H, Keyvani-Ghamsari S, Ur Rahman S

Autism Spectrum Disorder (ASD) as referred to herein may be considered according to the Diagnostic and Statistical Manual of Mental Disorders, 5 th Edition (DSM-5), which is herein incorporated by referenced in its entirety