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Feature · Product Review
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In addition, ACSL4 knockout (KO) cells were resistant to RSL3, an inhibitor of GPX4 and an inducer of ferroptosis, while ACSL4 overexpression in ferroptosis-resistant cells (such as Lymph Node Carcinoma of the prostate [LNCap] and K562 [human lymphoblast cells of chronic myelogenous leukaemia]) significantly increased their sensitivity to ferroptosis

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Recent Research Studies: Recent research on DSED has provided valuable insights into the disorder, including: Effectiveness of Therapeutic Interventions: Studies comparing different therapeutic modalities to determine the most effective approaches for treating DSED

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Pathway analysis demonstrated that OVX associated highly affected pathways include alanine, aspartate and glutamate metabolism, TCA-cycle, purine metabolism, taurine and hypotaurine metabolism and pentose phosphate pathway (Table 2)

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After blocked with 10% goat serum for 30 min, the cells were incubated with primary antibody (Claudin1, 1:100) overnight at 4 C

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