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Healthcare providers who may perform lumbar ESIs include: Advertisement Before your lumbar ESI, its important to tell your healthcare provider if youre pregnant or might be pregnant due to the likely use of fluoroscopy imaging (a type of X-ray imaging) during the procedure

That may show up as achy joints, skin breakouts, or headaches

Referral to secondary care may be appropriate if the cause remains unclear, if neurological symptoms are present, or if initial treatment proves ineffective

The pharma has previously announced that REDEFINE 1 is expected to read out by the end of the year, while data from REDEFINE 2 are expected in the first half of 2025

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