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Hoffmann M, Kleine-Weber H, Schroeder S et al (2020) SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor

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Consistently, hemin-induced HO-1 expression provides cardioprotective activity, attenuating ischemic-induced cardiomyocytes senescence and preventing myocardial infarction (150)