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In spermatozoa, 0.79 and 0.14 femtograms (i.e., 1015 g) of Se are present in the midpiece and head of spermatozoa, respectively, with 5.6 times higher Se levels and 18 times lower Se concentrations in the midpiece than in the head (85, 92)

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Future research should explore these mechanisms further and focus on developing therapeutic strategies to protect reproductive health in diabetic patients

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Since we previously found that ser/gly rewired tumors produce and secrete high levels of pathway metabolites into the circulation, we hypothesized that metabolomic analysis of blood plasma samples from patients with NSCLC could give valuable insight into ser/gly metabolic rewiring in tumor cells in response to RT [24]