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Rich et al

The most commonly observed adverse events (incidence of 5% and twice that of placebo) were oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation and fecal incontinence

This nitrogen atom contains a lone pair of electrons that enables it to act as a nucleophile

Specifically, small apoAI containing HDL particles are the most efficient at accepting lipid hydroperoxides, which are reduced to their inactive lipid hydroxides via oxidation of the methionine residues in apoA-I (850)

Besides the FSP1-CoQ pathway, recent evidence has revealed an alternative ferroptosis defense mechanism involving dihydroorotate dehydrogenase (DHODH) and coenzyme Q10

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