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10.1073/pnas.78.11.6858 Proc

If you have variants below, read more here, and then use caution when combining with medications that are metabolized through that pathway

PMID: 41711093

Clinical genetics of amyotrophic lateral sclerosis: what do we really know

Specifically, oxidation is when a molecule loses electrons, and reduction is when a molecule gains electrons

Part 4 Section 11 Management Strategy 3: Medications Atropine Learning Objectives Atropine: Mechanism of Action Diagnostic Use: The Atropine Challenge Atropine: Available Forms (Optional Reading) Atropine: Stability of Solution (Optional Reading) Atropine: Route of Administration Misconception Reality Reasons Why Signs of Atropinism Are Not the Appropriate End Point to Guide Atropine Treatment Atropine Dose Misconception Reality Total Doses of Atropine in Poisoning with Organophosphorus Compounds (Optional Reading) Extremely High Total Doses of Atropine May be Needed in Suicidal Ingestions of Organophosphorus Compounds (Optional Reading) Nerve Agents Require Lower Total Doses of Atropine (Optional Reading) Carbamates Require Lower Doses (Optional Reading) Atropine: Low Incidence of Adverse Effects Alternatives to Atropine (Optional Reading) Key Points Progress Check Upon completion of this section, you should be able to identify the: Mechanism by which atropine counters the effects of the cholinergic toxidrome