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5-amino-1MQ (5-amino-1-methylquinolinium iodide) is a small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT), the enzyme that methylates nicotinamide using S-adenosylmethionine (SAM)

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Their work found and described several selective NNMT inhibitors, including 5-amino-1-methylquinolinium derivatives

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