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Dual antiplatelet therapy, including the traditional anticoagulant aspirin in combination with an ADP inhibitor or the platelet P2Y12 ADP blocker (prasugrel and ticagrelor), has been used for coronary artery disease patients

Furthermore, Nrf2 promoter hypermethylation is observed in both COPD patients and CSE-treated HBE cells, resulting in NRF2 downregulation, inhibited GPX4 expression and ferroptosis occurrence[21]

Glutathione is heavily concentrated in the liver, and during alcohol metabolism is consumed rapidly as it neutralises toxic by-products and free radicals

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