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Principally, I only cover biomedicine (even though I was a full-time emergency physician for twenty years) if it's a story that involved me personally (or unless it's an under-reported blockbuster, eg see my write-ups on French artificial heart maker Carmat and on French artificial retina maker Pixium, developed by Stanford's Prof

Stress signals for apoptosis: ceramide and c-Jun kinase

In an ischemic stroke mouse model, reactive astrocytes were linked to vascular repair, as they increased the expression of genes related to angiogenesis

However, to bind IREs, these cysteines need to be reduced by Trx1 [13,16]

While some replicated the fructose effect (195), others found no clinical benefit and noted potential harm, including elevated serum uric acid and lactate levels (196)

Impact statement Recently advanced understanding of pathogenesis of atherosclerosis transformed the disease treatment approach from slowing its progression to promoting the regression of atherosclerosis