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Future studies are necessary to deeply explore the direct association between copper and the EGFR pathway, providing new ideas for the combined application of copper-targeted therapy and EGFR inhibitors (147)

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Secondly, ES can inhibit biofilm formation by disrupting bacterial cell membrane structures or metabolic processes, increasing local metabolic activity and tissue oxidation, thus directly inhibiting bacterial growth and reproduction (Perez-Roa et al., 2006)

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GHK-Cu can upregulate genes linked to collagen and elastin

Mortality, morbidity, and weight of mice will be monitored for 5 days after injection