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Semaglutide is one type of active ingredient in glucagon-like peptide-1 (GLP-1) receptor agonist drugs, widely known as type 2 diabetes treatment (Ozempic) and weight loss medication for obesity (Wegovy)

Cytokine storm or cytokine release syndrome (CRS), damage and depletion of bystander healthy cells, so-called on-target/off-tumor toxicity, tumor lysis syndrome (TLS), graft versus host disease (GVHD), neurotoxicity, and anaphylactic shock are prevalent complications of CAR-T cell therapy leading to multi-organ failure [10, 11]

10.3389/fgene.2021.653209 132 HeW.ZhuX.XinA.ZhangH.SunY.XuH.et al (2022)

Pathophysiology The clinical picture of AHA in a G6PD-deficient child is a vivid expression of the fact that, as we know already, hemolysis results from the action of an exogenous factor on latently but intrinsically abnormal red blood cells

SAL seems to enhance insulin resistance via activating a route that links mitochondria to AMPK, PI3K, Akt, and GSK-3

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