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For instance, the superoxide cannot be detected using DCFDA at all (Kalyanaraman et al

This table systematically maps the major pathways disrupted in adipocyte dysfunction, tracking changes from molecular mechanisms to systemic consequences

J.BarrientosT.et al (2015)

3 Ferroptosis: a novel player in depression pathogenesis Dixon and his team introduced the concept of ferroptosis in 2012, characterizing it as an iron-dependent mode of programmed cell death marked by the build-up of lipid hydroperoxides (Dixon et al., 2012)

This phenomenon resulted in glycogen accumulation and glucose uptake, which supported the pentose phosphate pathway to maintain NADPH synthesis, leading to cell survival and growth

Autologous stem cells, sourced from the patient, show promise for future clinical use due to their safety and immunogenicity benefits