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The first one involves irreversible damage to the ETC, possibly through TTC5 upregulation, resulting in ATP loss, increased mitochondrial superoxide production and caspases 3/7 activation, and subsequent apoptosis

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Central & Peripheral Anti-Obesity Targets (PMC) AOD-9604 RCT summary and mechanistic overview PubMed Metabolic studies of AOD-9604 in obese rodents (oral dosing, fat oxidation) Related research, protocols, and guides Explore the available research context, protocol variants or comparisons, and practical guides

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