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Temperature excursions above 8C or storage beyond 28 days compromise bioactivity regardless of solution appearance

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Thus, the chemical nature of the particulates, for example if a hydrophobic particulate is used, can contribute to impeding the flow of liquid diffusion across an inner layer to an outer layer surface boundary

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[DOI] [PubMed] [Google Scholar] Grimshaw MJ, Wilson JL, Balkwill FR