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healthy-adult study established that the albumin-binding version produces sustained, dose-dependent GH and IGF-I elevation, with a multi-day half-life

(2017) 2:e89160

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In STEP 1 [1] , the largest trial with 1,961 participants [1] , patients receiving semaglutide 2.4 mg weekly achieved an average weight loss of 14.9% over 68 weeks, compared to 2.4% with placebo (Wilding et al., NEJM, 2021)

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