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doi: 10.1046/j.1365-2672.2003.02030.x 138 CutlerRRWilsonP

After incubation for 30 min at 37 C, samples were shock-frozen in liquid nitrogen

doi: 10.1038/srep44701 139 LingL.RaikhelA

While orally administered drugs need to undergo stomach acid breakdown, intestinal absorption, and first-pass metabolism in the liver, all of which can reduce the bioavailability of the drug and affect its ability to reach the lymph nodes, thus, it is generally few used for lymph node administration [47]