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Four -ketoacid dehydrogenase complexes ( Figure 4 ), including: (i) the pyruvate dehydrogenase complex that catalyzes the conversion of pyruvate to acetyl-coenzyme A (CoA), an important substrate for energy production via the citric acid cycle

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It's important to be aware of these interactions if you are taking any of the following long-term: Acid-Reducing Drugs : Medications like Proton Pump Inhibitors (PPIs) (e.g., omeprazole) and H2 Receptor Antagonists (e.g., cimetidine) reduce the stomach acid needed to release B12 from food

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